A query that has lingered because the 2009 mass vaccination marketing campaign towards pandemic H1N1 swine flu is whether or not seasonal influenza vaccination may make pandemic infections worse or extra prevalent.1
Early on within the COVID-19 pandemic, Dr. Michael Murray, naturopath and creator, confirmed what Judy Mikovits, Ph.D., informed me in her second interview with me, particularly that seasonal influenza vaccinations might have contributed to the dramatically elevated COVID-19 mortality seen in Italy. In a weblog put up, he identified that Italy had launched a brand new, stronger kind of flu vaccine, known as VIQCC, in September 2019:2
“Most accessible influenza vaccines are produced in embryonated rooster eggs. VIQCC, nonetheless, is produced from cultured animal cells reasonably than eggs and has extra of a ‘boost’ to the immune system consequently.
VIQCC additionally comprises 4 sorts of viruses — 2 kind A viruses (H1N1 and H3N2) and a pair of kind B viruses.3 It appears to be like like this ‘super’ vaccine impacted the immune system in such a approach to enhance coronavirus an infection via virus interference …”
Vaccines and Virus Interference
The sort of virus interference Murray was referring to had been proven to be at play throughout the 2009 pandemic swine flu. A 2010 assessment4,5 in PLOS Medicine, led by Dr. Danuta Skowronski, a Canadian influenza knowledgeable with the Centre for Disease Control in British Columbia, discovered the seasonal flu vaccine elevated individuals’s danger of getting sick with pandemic H1N1 swine flu and resulted in additional severe bouts of sickness.
People who acquired the trivalent influenza vaccine throughout the 2008-2009 flu season have been between 1.4 and a pair of.5 occasions extra seemingly to get contaminated with pandemic H1N1 within the spring and summer season of 2009 than those that didn’t get the seasonal flu vaccine.
To double-check the findings, Skowronski and different researchers carried out a follow-up examine on ferrets. Their findings have been introduced on the 2012 Interscience Conference on Antimicrobial Agents and Chemotherapy. At the time, Skowronski commented on her group’s findings, telling MedPage Today:6
“There may be a direct vaccine effect in which the seasonal vaccine induced some cross-reactive antibodies that recognized pandemic H1N1 virus, but those antibodies were at low levels and were not effective at neutralizing the virus. Instead of killing the new virus it actually may facilitate its entry into the cells.”
In all, 5 observational research carried out throughout a number of Canadian provinces discovered an identical outcomes. These findings additionally confirmed preliminary information from Canada and Hong Kong. As Australian infectious illness knowledgeable professor Peter Collignon informed ABC News:7
“Some attention-grabbing information has develop into accessible which means that should you get immunized with the seasonal vaccine, you get much less broad safety than should you get a pure an infection …
We could also be perversely setting ourselves up that if one thing actually new and nasty comes alongside, that individuals who have been vaccinated might the truth is be extra inclined in contrast to getting this pure an infection.”
A examine8,9 printed within the January 10, 2020, situation of the journal Vaccine additionally discovered individuals have been extra seemingly to get some type of coronavirus an infection if that they had been vaccinated towards influenza. As famous on this examine, titled “Influenza Vaccination and Respiratory Virus Interference Among Department of Defense Personnel During the 2017-2018 Influenza Season:”
“Receiving influenza vaccination may increase the risk of other respiratory viruses, a phenomenon known as virus interference … This study aimed to investigate virus interference by comparing respiratory virus status among Department of Defense personnel based on their influenza vaccination status.”
While seasonal influenza vaccination didn’t elevate the danger of all respiratory infections, it was the truth is “significantly associated with unspecified coronavirus” (that means it didn’t particularly point out SARS-CoV-2, which was nonetheless unknown on the time this examine was carried out) and human metapneumovirus (hMPV10).
Remember, SARS-CoV-2 is one in all seven completely different coronaviruses identified to trigger respiratory sickness in people.11 Four of them — 229E, NL63, OC43 and HKU1 — trigger signs related to the widespread chilly.
OC43 and HKU112 are additionally identified to trigger bronchitis, acute exacerbation of continual obstructive pulmonary illness and pneumonia in all age teams.13 The different three human coronaviruses — that are able to inflicting extra severe respiratory sickness — are SARS-CoV, MERS-CoV and SARS-CoV-2.
Service members who had acquired a seasonal flu shot throughout the 2017-2018 flu season have been 36% extra seemingly to contract coronavirus an infection and 51% extra seemingly to contract hMPV an infection than unvaccinated people.14,15
Influenza Vaccination Linked to Higher COVID Death Rates
October 1, 2020, professor Christian Wehenkel, an instructional editor for PeerJ, printed an information evaluation16 in that very same journal, wherein he stories discovering a “positive association between COVID-19 deaths and influenza vaccination rates in elderly people worldwide.”
In different phrases, areas with the best vaccination charges amongst aged individuals additionally had the best COVID-19 loss of life charges. To be honest, the writer’s be aware factors out that correlation doesn’t vital equal causation:
“What does that imply? By approach of instance, in some cities elevated ice cream gross sales correlate with elevated homicide charges. But that does not imply that if extra ice lotions are bought, then homicide charges will enhance. There is another issue at play — the climate temperature.
Similarly, this text shouldn’t be taken to recommend that receiving the influenza vaccination ends in an elevated danger of loss of life for a person with COVID-19 as there could also be many confounding elements at play (together with, for instance, socioeconomic elements).”
That mentioned, one of many causes for the evaluation was to double-check whether or not the info would assist stories claiming that seasonal influenza vaccination was negatively correlated with COVID-19 mortality — together with one which discovered areas in Italy with greater vaccination charges amongst elders had decrease COVID-19 loss of life charges.17 “A negative association was expected,” Wehenkel writes in PeerJ. But that’s not what he discovered:
“Contrary to expectations, the present worldwide analysis and European sub-analysis do not support the previously reported negative association between COVID-19 deaths (DPMI) [COVID-19 deaths per million inhabitants] and IVR [influenza vaccination rate] in elderly people, observed in studies in Brazil and Italy,” the creator famous.18
“To decide the affiliation between COVID-19 deaths and influenza vaccination, accessible information units from international locations with greater than 0.5 million inhabitants have been analyzed (in complete 39 international locations).
To precisely estimate the affect of IVR on COVID-19 deaths and mitigate results of confounding variables, a complicated rating of the significance of various variables was carried out, together with as predictor variables IVR and a few probably essential geographical and socioeconomic variables in addition to variables associated to non-pharmaceutical intervention.
The associations have been measured by non-parametric Spearman rank correlation coefficients and random forest capabilities.
The outcomes confirmed a constructive affiliation between COVID-19 deaths and IVR of individuals ≥65 years-old. There is a big enhance in COVID-19 deaths from japanese to western areas on the planet. Further exploration is required to clarify these findings, and extra work on this line of analysis might lead to prevention of deaths related to COVID-19.”
What Might Account for Vaccination-Mortality Link?
In the dialogue part of the paper, Wehenkel factors out that earlier explanations for a way flu vaccination may scale back COVID-19 deaths are usually not supported by the info he collected.
For instance, he cites analysis attributing the useful impact of flu vaccination to improved prevention of influenza and SARS-CoV-2 coinfections, and one other that urged the flu vaccine may enhance SARS-CoV-2 clearance.
These arguments “cannot explain the positive, direct or indirect relationship between influenza vaccination rates and both COVID-19 deaths per million inhabitants and case fatality ratio found in this study, which was confirmed by an unbiased ranking variable importance using Random Forest models,” Wehenkel says.19 (Random Forest refers to a most well-liked classification algorithm utilized in information science to mannequin predictions.20) Instead, he affords the next hypotheses:21
“The influenza vaccine might enhance influenza immunity on the expense of diminished immunity to SARS-CoV-2 by some unknown organic mechanism, as urged by Cowling et al. (2012)22 for non-influenza respiratory virus.
Alternatively, weaker short-term, non-specific immunity after influenza viral an infection may trigger this constructive affiliation due to stimulation of the innate immune response throughout and for a short while after an infection.23,24
People who had acquired the influenza vaccination would have been protected towards influenza however not towards different viral infections, due to diminished non-specific immunity within the following weeks,25 in all probability brought on by virus interference.26,27,28
Although present human vaccine adjuvants have a excessive degree of security, particular adjuvants in influenza vaccines also needs to be examined for opposed reactions, reminiscent of moreover elevated irritation indicators29 in COVID-19 sufferers with already strongly elevated irritation.”30
The Flu Vaccine Paradox
Since Wehenkel’s evaluation focuses on the flu vaccine’s impression on COVID-19 mortality among the many aged, it may be helpful to check out information introduced at a World Health Organization workshop in 2012. On web page 6 of the workshop presentation31 in query, the presenter discusses “a paradox from trends studies” exhibiting that “influenza-related mortality increased in U.S. elderly while vaccine coverage rose from 15% to 65%.”
On web page 7, he additional notes that whereas a decline in mortality of 35% can be anticipated with that enhance in vaccine uptake, assuming the vaccine is 60% to 70% efficient, the mortality price has risen as an alternative, though not precisely in tandem with vaccination protection.
On web page 10, one other paradox is famous. While observational research declare the flu vaccine reduces winter mortality danger from any trigger by 50% among the many aged, and vaccine protection among the many aged rose from 15% to 65%, no mortality decline has been seen among the many aged throughout winter months.32,33
Seeing how the aged are the most certainly to die due to influenza, and the flu accounts for five% to 10% of all winter deaths, a “50% mortality savings [is] just not possible,” the presenter states. He then goes on to spotlight research exhibiting proof of bias in research that estimate influenza vaccine effectiveness within the aged. When that bias is adjusted for, vaccine effectiveness amongst seniors is discouraging.
Interestingly, the doc factors out that immunologists have lengthy identified that vaccine effectiveness within the aged can be low, thanks to senescent immune response, i.e., the pure decline in immune operate that happens with age. This is why influenza “remains a significant problem in elderly despite widespread influenza vaccination programs,” the presenter notes.
Report All COVID-19 Vaccine Side Effects
My perception is that present COVID-19 “vaccines,” which use mRNA gene remedy know-how, are seemingly to do extra hurt than good in most individuals. There are many stories of aged in nursing properties dying inside hours or days of getting the vaccine. This is probably going due to an awesome inflammatory response.
If you’re aged and frail, or have a member of the family who’s aged and considering of getting the vaccine, I’d urge you to take a deeper dive into the accessible analysis, and to assessment the facet impact statistics earlier than making your choice.
Last however not least, should you or somebody you’re keen on have acquired a COVID-19 vaccine and are experiencing unwanted side effects, make sure to report it:34
- If you reside within the U.S., file a report on VAERS
- Report the harm on VaxxTracker.com, which is a nongovernmental opposed occasion tracker (you possibly can file anonymously should you like)
- Report the injury on the CHD website