From improving cancer treatments to saving the bees, these are the companies in IndieBio’s latest class – TechCrunch

Ultra-precise cancer therapies! Human-like hair grown from crops! A method to doubtlessly save the bees!

The spectrum of companies popping out of IndieBio has all the time been fairly wild, and its latest batch undoubtedly doesn’t disappoint.

As the early-stage, biology-focused accelerator arm of SOSV, IndieBio offers the companies in its program $250,000+, mentorship and full entry to a biology lab to deliver their concepts to life.

When founder Arvind Gupta left the accelerator final 12 months to join the venture capital fund Mayfield, Mayfield and IndieBio partnered to type the Genesis Consortium, which affords IndieBio companies an extra $250,000 in non-compulsory funding.

IndieBio initially operated solely out of San Francisco, with the accelerator increasing simply final 12 months to embody a New York cohort that runs in parallel. The SF program is led by Managing Director Po Bronson, whereas the New York program is led by Managing Director Stephen Chambers.

With its Demo Day nonetheless a methods out, IndieBio gave us a peek at the groups at the moment going by the program. It’s value noting that IndieBio intentionally invests very early — in many instances, even earlier than it’s solely clear whether or not or not the scientific ideas behind an organization are totally possible. “Our program is our diligence,” Bronson tells me. The purpose is to show out ideas — and determine how to flip them into large companies — for a whole lot of 1000’s of {dollars}, fairly than tens of millions. “We’re biting off the risk, and de-risking it for the next investors in line.”

Here are the companies at the moment in every program, alphabetically:

New York

Beemmunity: Humans want bees in order to survive, however bee populations are plummeting, with one in all the most important causes believed to be publicity to neurotoxic pesticides. Pitched as “pesticide protection for bees,” Beemmunity is engaged on a “micro-sponge” that, after being ingested by a bee, captures these neurotoxins and eliminates them as waste. Expected to enter subject trials quickly.

Brickbuilt Therapeutics: A biotherapeutic lozenge meant to assist stop and deal with issues like gum illness and thrush.


Bucha Leather Synthetic, animal-free leather-based grown from bacterial nanocellulose. Their course of permits them to make “massive mats” of fabric that may be produced in weeks.

Free to Feed: If an toddler proves allergic to one thing in their mom’s breastmilk, figuring out precisely what they’re allergic to is usually a lengthy and extremely irritating course of. Free to Feed is creating check strips that determine totally different meals proteins in breast milk, serving to breastfeeding moms higher decide what proteins are main to an allergic response.

Gypsy Basin Genomics: Developing a check, easy sufficient to be administered as a gargle-and-a-spit throughout a dentist go to, that may detect at an early stage the oral cancers attributable to HPV.

Harmony Baby Nutrition: Pitched as “the only dairy-free, allergy-free, and environmentally friendly baby formula,” Harmony is producing toddler formulation that “closely mirror human breast milk.”

MicroTERRA: Using duckweed water lentils to convert fish-farm wastewater into protein. The duckweed helps to purify the fish waste water because it grows; as soon as grown, this “lemna protein concentrate” can be utilized as a supply of protein in animal feed.

Nyoka Design Labs: Non-toxic, biodegradable and recyclable glowsticks powered by bioluminescence.

Sequential Skin: Wipe your face with their pores and skin check package, ship it to their lab, and get a full report on the merchandise that ought to work effectively along with your pores and skin’s microbiome.

Stembionix: With private stem cell banking in thoughts, Stembionix is creating a “mailable bioreactor system” that may enable for the transporting of stem cells with out the freezing/thawing that complicates issues and may negatively impression viability.

San Francisco

Aja Labs: Pitched as the “beyond meat of hair extensions,” Aja Labs needs to use crops to develop fibers that appear and feel like human hair, doubtlessly eliminating the want for chemical-heavy synthetics or human hair in the manufacturing of hair extensions. Using interpretable machine studying to determine genes (and what stated genes do) in crops at a a lot quicker tempo to assist develop higher crops.

California Cultured: Lab-grown cocoa. The firm says it may develop cocoa that’s much less bitter, and as such requires far much less sugar to be tasty.

Canaery: Aiming to “do for scent what machine vision has done for sight,” Canaery is constructing a neural interface for analyzing an object’s “scent fingerprint” to determine harmful compounds at locations like ports and inspection factors with out (or in addition to) x-rays or cameras.

Capra Biosciences: Finding methods to flip the in any other case detrimental biofilms that may develop throughout fermentation into merchandise like motor oil or retinol for cosmetics.

Lypid: Developing vegan oils that behave like animal fat, melting at the identical temperature and offering the identical mouthfeel, to additional enhance plant-based meats.

OncoPrecision: Building a quicker method to assist oncologists decide which cancer medication (of a whole lot) will work greatest for a affected person by making use of medication to patient-derived cells, with the purpose of discovering the greatest drug inside 7-14 days.

Ozone Bio: Using useless cell fermentation (or “Zombiezymes”) to produce nylon in a greener method.

Panacea Longevity: Aiming to replicate the well being advantages of fasting… with out fasting. Identifying dietary compounds that may “mimic the body’s natural response to fasting” and develop them right into a complement.

Prolific Machines: High-resolution management of cell differentiation. In lab-grown meat, for instance, one might use their tech to decide what bits of a steak are muscle tissue, fats, and so forth.

Proteinea: Using fly larva to develop “pharma-grade proteins” to be used in medication cheaper and extra rapidly.

Sundial Foods: Bringing “skin” to plant-based hen, starting with a coating that can enable for plant-based hen wings.

vertical oceans

Vertical Oceans: Taking the idea of vertical farming and making use of it to seafood, Vertical Oceans is engaged on environment friendly, low-waste, stackable towers to make the manufacturing of shrimp extra sustainable.

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